themoralbrain
Assay / exosome / PCR

Cellulaire veroudering bij hepatocellulair carcinoom

- juni 28, 2021 - Jan

Cellulaire veroudering bij hepatocellulair carcinoom geïnduceerd door een lang niet-coderend RNA-gecodeerd peptide PINT87aa door FOXM1-gemedieerde PHB2 te blokkeren

Rationale:  Onlangs is aangetoond dat lange niet-coderende RNA’s (lncRNA’s), waarvan bekend is dat ze betrokken zijn bij de progressie van kanker bij de mens, coderen voor peptiden met biologische functies, maar de rol van door lncRNA gecodeerde peptiden bij cellulaire veroudering is grotendeels onontgonnen. We rapporteerden eerder de tumor-onderdrukkende rol van PINT87aa, een peptide dat wordt gecodeerd door het lange intergene niet-eiwit coderende RNA, p53-geïnduceerde transcript ( LINC-PINT).  Hier hebben we de rol van PINT87aa bij cellulaire senescentie van hepatocellulair carcinoom (HCC) onderzocht.

Methoden:  We onderzochten de functies van PINT87aa en afgeknotte PINT87aa  in vitro  door celproliferatie te volgen en voerden flowcytometrie uit, senescentie-geassocieerde β-galactosidase-kleuring, JC-1-kleuring die indicatief is voor mitochondriaal membraanpotentieel, de verhouding van het overlappende gebied van lichte keten Three bèta ( LC3B) en mitochondriale sondes en de verhouding van lysosomaal geassocieerd membraaneiwit 1 (LAMP1) overlapt met cytochroom c-oxidase-subeenheid 4I1 (COXIV) die mitofagie aangeeft. PINT87aa en afgeknotte PINT87aa-functies  in vivo werden geverifieerd door subcutaan getransplanteerde tumoren in naakte muizen. De mogelijke binding tussen PINT87aa en forkhead subject M1 (FOXM1) werd voorspeld door middel van structurele analyse en geverifieerd door co-immunoprecipitatie en immunofluorescentie co-lokalisatie. Rescue-experimenten werden  in vivo en in vitro uitgevoerd  na overexpressie van FOXM1. Verder werden chromatine-immunoprecipitatie, polymerasekettingreactie en dual-luciferase-reportergentest uitgevoerd om FOXM1-binding aan de prohibitine 2  ( PHB2 ) -promotor te valideren  .

Resultaten:  PINT87aa was necessary verhoogd in het door waterstofperoxide geïnduceerde HCC-celsenescentiemodel. Overexpressie van PINT87aa induceerde groeiremming, cellulaire veroudering en verminderde mitofagie  in vitro  en  in vivo . Daarentegen zou FOXM1 gain-of-function het aandeel senescente HCC-cellen gedeeltelijk kunnen verminderen en de mitofagie kunnen verbeteren. PINT87aa-overexpressie had geen invloed op de expressie van FOXM1 zelf, maar verminderde die van zijn doelwitgenen die betrokken zijn bij celcyclus en proliferatie, met establish  PHB2, die betrokken was bij mitofagie en getranscribeerd door FOXM1. Structurele analyse gaf aan dat PINT87aa kon binden aan het DNA-bindende domein van FOXM1, wat werd bevestigd door co-immunoprecipitatie en immunofluorescentie co-lokalisatie. Verder hebben we aangetoond dat de afgeknotte vorm van 2 tot 39 aminozuren van het peptide effecten uitoefende die vergelijkbaar waren met de volledige vorm.

Conclusie:  Onze studie stelde de rol enormous van PINT87aa als een nieuwe biomarker en een belangrijke regulator van cellulaire veroudering in HCC en identificeerde PINT87aa als een potentieel therapeutisch doelwit voor HCC.

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UCP5 Polyclonal Antibody
ABP60850-02ml 0.2ml
EUR 414
Description: A polyclonal antibody for detection of UCP5 from Human, Mouse. This UCP5 antibody is for WB, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human UCP5 protein

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EF004049 96 Tests
EUR 689

Substance P reversed sequence Peptide
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  • 10 mg
  • 25 mg
  • 5 mg

Erythropoietin Mimetic Peptide Sequence 20
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Description: Sum Formula: C72H99N17O17S2; CAS# [203397-62-0] net

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Description: Sum Formula: C72H99N17O17S2; CAS# [203397-62-0] net

Custom production of antibodies in 5 Rats using customer supplied antigen (std 63 days protocol)
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Rat C-Peptide ELISA Kit
RD-C-Peptide-Ra-48Tests 48 Tests
EUR 465

Rat C-Peptide ELISA Kit
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EUR 643

Rat C-Peptide ELISA Kit
DLR-C-Peptide-Ra-48T 48T
EUR 467
Description: A competitive inhibition quantitative ELISA assay kit for detection of Rat C-Peptide in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Rat C-Peptide ELISA Kit
DLR-C-Peptide-Ra-96T 96T
EUR 605
Description: A competitive inhibition quantitative ELISA assay kit for detection of Rat C-Peptide in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Rat C-Peptide ELISA Kit
RDR-C-Peptide-Ra-48Tests 48 Tests
EUR 486

Rat C-Peptide ELISA Kit
RDR-C-Peptide-Ra-96Tests 96 Tests
EUR 672

(PPPPNAND)3 peptide (repeat-sequence peptide of the P. berghei circumsporozoite protein, CSP) control/blocking peptide
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Rat Calnuc Blocking Peptide
33R-2673 100 ug
EUR 180
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of NUCB1 antibody, catalog no. 70R-1118

NET Blocking Peptide (Rat)
30R-AN036 100 ug
EUR 241
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UCP3 Blocking Peptide (Rat)
30R-AU003 100 ug
EUR 256
Description: A synthetic UCP3 Blocking peptide for use as a blocking control in assays to test for specificity of UCP3 antibody, catalog no. 70R-UR005

Influenza A virus (H5N1) matrix protein 2 hybrid sequence Control/blocking peptide
M2E11-P 100 ug
EUR 164

(NVDP)4 peptide (minor repeat-sequence peptide of the P. falciparum circumsporozoite protein, CSP) control/blocking peptide
NVDP41-P 100 ug
EUR 164

(DRAAGQPAG)3 (repeat-sequence peptide of the P. vivax circumsporozoite protein, CSP) control/blocking peptide
DRAA31-P 100 ug
EUR 164

Rabbit Anti-Rat Uncoupling Protein 5 (UCP5) antiserum # 1
UCP51-S 100 ul
EUR 457

Rat GTRAP41 Control/blocking peptide
GTRAP41-P 100 ug
EUR 164

Rat GTRAP48 Control/blocking peptide
GTRAP48-P 100 ug
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C-Peptide Blocking Peptide
3277BP-50
EUR 153

Human, mouse, rat connexin 43 and 37 hemi-channel blocking peptide (GAP27 domain with conserved sequence SRPTEK)
Cx2703-P-1 1 mg
EUR 263

Human, mouse, rat connexin 43 and 37 hemi-channel blocking peptide (GAP27 domain with conserved sequence SRPTEK)
Cx2703-P-5 5 mg
EUR 773

Rabbit Anti-Rat Uncoupling Protein 5 (UCP5) IgG #1, aff pure
UCP51-A 100 ug
EUR 482

Rat UT2 Control/blocking peptide #1
RUT21-P 100 ug
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Rat Syntenin Control/blocking peptide #1
SDB11-P 100 ug
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Rat Nephrin Control/blocking peptide #1
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Rat Amylin Control/blocking peptide # 3
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Rat AVP V1b Control/blocking peptide
AVP1B13-P 100 ug
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Rat AVP-V2 Control/blocking peptide
AVPV21-P 100 ug
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Rat EAAT4 Control/blocking peptide #1
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Dopamine Receptor 2 Blocking Peptide (Rat)
30R-AD007 100 ug
EUR 241
Description: A synthetic Dopamine Receptor 2 Blocking peptide for use as a blocking control in assays to test for specificity of Dopamine Receptor 2 antibody, catalog no. 70R-DR001

Canine C-Peptide ELISA Kit
RD-C-Peptide-c-48Tests 48 Tests
EUR 533

Canine C-Peptide ELISA Kit
RD-C-Peptide-c-96Tests 96 Tests
EUR 740

Human C-Peptide ELISA Kit
RD-C-Peptide-Hu-48Tests 48 Tests
EUR 387

Human C-Peptide ELISA Kit
RD-C-Peptide-Hu-96Tests 96 Tests
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Mouse C-Peptide ELISA Kit
RD-C-Peptide-Mu-48Tests 48 Tests
EUR 446

Mouse C-Peptide ELISA Kit
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EUR 615

Canine C-Peptide ELISA Kit
DLR-C-Peptide-c-48T 48T
EUR 527
Description: A competitive inhibition quantitative ELISA assay kit for detection of Canine C-Peptide in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Canine C-Peptide ELISA Kit
DLR-C-Peptide-c-96T 96T
EUR 688
Description: A competitive inhibition quantitative ELISA assay kit for detection of Canine C-Peptide in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Human C-Peptide ELISA Kit
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EUR 398
Description: A competitive inhibition quantitative ELISA assay kit for detection of Human C-Peptide in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Human C-Peptide ELISA Kit
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EUR 511
Description: A competitive inhibition quantitative ELISA assay kit for detection of Human C-Peptide in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Mouse C-Peptide ELISA Kit
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EUR 450
Description: A competitive inhibition quantitative ELISA assay kit for detection of Mouse C-Peptide in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Mouse C-Peptide ELISA Kit
DLR-C-Peptide-Mu-96T 96T
EUR 582
Description: A competitive inhibition quantitative ELISA assay kit for detection of Mouse C-Peptide in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Canine C-Peptide ELISA Kit
RDR-C-Peptide-c-48Tests 48 Tests
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RDR-C-Peptide-c-96Tests 96 Tests
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Mouse C-Peptide ELISA Kit
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CD39 Blocking Peptide
P10103 20 ug Blocking Peptide
EUR 146

P2X3 Blocking Peptide
P10108 100 ug Blocking Peptide
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CXCL1 Blocking Peptide
20-abx061039
  • EUR 286.00
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  • 1 mg
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p21 Blocking Peptide
20-abx061043
  • EUR 286.00
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  • 1 mg
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Dyskerin Blocking Peptide
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  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

ZNF265 Blocking Peptide
20-abx061051
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

CDK11B Blocking Peptide
20-abx061053
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

HMGB2 Blocking Peptide
20-abx061056
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

ZFP36L2 Blocking Peptide
20-abx061059
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

CBP20 Blocking Peptide
20-abx061060
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

FOXE3 Blocking Peptide
20-abx061063
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

CBFB Blocking Peptide
20-abx061064
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

MAPKAPK3 Blocking Peptide
20-abx061065
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

MOB3C Blocking Peptide
20-abx061067
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

DPF2 Blocking Peptide
20-abx061068
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

TAF15 Blocking Peptide
20-abx061069
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

FAM84B Blocking Peptide
20-abx061070
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

GTF2IRD1 Blocking Peptide
20-abx061071
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

COL19A1 Blocking Peptide
20-abx061072
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

CYP2W1 Blocking Peptide
20-abx061073
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

RAD21 Blocking Peptide
20-abx061075
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

PSMC3 Blocking Peptide
20-abx061076
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

PSMD11 Blocking Peptide
20-abx061077
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

MRPS9 Blocking Peptide
20-abx061078
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

MRPL41 Blocking Peptide
20-abx061079
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

MRPL48 Blocking Peptide
20-abx061080
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

RPS12 Blocking Peptide
20-abx061081
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

RPS13 Blocking Peptide
20-abx061082
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

ACSS1 Blocking Peptide
20-abx061084
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

AKR1C2 Blocking Peptide
20-abx061085
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

ACER3 Blocking Peptide
20-abx061086
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

ATP5I Blocking Peptide
20-abx061087
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

ATP5C1 Blocking Peptide
20-abx061088
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

CNTROB Blocking Peptide
20-abx061089
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

CEP78 Blocking Peptide
20-abx061090
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

DMGDH Blocking Peptide
20-abx061093
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

EIF3D Blocking Peptide
20-abx061095
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

FUBP3 Blocking Peptide
20-abx061096
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

GHITM Blocking Peptide
20-abx061097
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

SAR1B Blocking Peptide
20-abx061098
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

NXPH3 Blocking Peptide
20-abx061101
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

PP15 Blocking Peptide
20-abx061102
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

LONP2 Blocking Peptide
20-abx061104
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

PEX10 Blocking Peptide
20-abx061105
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

PABPC5 Blocking Peptide
20-abx061106
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

PRPF39 Blocking Peptide
20-abx061107
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

PPM1K Blocking Peptide
20-abx061108
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

RSAD1 Blocking Peptide
20-abx061109
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

Renin Blocking Peptide
20-abx061110
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

SH2D2A Blocking Peptide
20-abx061113
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

SCN4B Blocking Peptide
20-abx061114
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

SFRS15 Blocking Peptide
20-abx061115
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

TCEAL1 Blocking Peptide
20-abx061116
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

TMBIM4 Blocking Peptide
20-abx061117
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

WIPF1 Blocking Peptide
20-abx061118
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

ZFYVE19 Blocking Peptide
20-abx061119
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

ZNT1 Blocking Peptide
20-abx061120
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

BNIP3 Blocking Peptide
20-abx061122
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

SHIP2 Blocking Peptide
20-abx061126
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

CD248 Blocking Peptide
20-abx061132
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

CD225 Blocking Peptide
20-abx061133
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

CD276 Blocking Peptide
20-abx061134
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

CD300d Blocking Peptide
20-abx061135
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

GPR10 Blocking Peptide
20-abx061136
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

GPCR135 Blocking Peptide
20-abx061137
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

STAT5 Blocking Peptide
20-abx061148
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

TGFBR2 Blocking Peptide
20-abx061149
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

ABL1 Blocking Peptide
20-abx061151
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

SPHK2 Blocking Peptide
20-abx061153
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

RPS6KC1 Blocking Peptide
20-abx061156
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

MMTAG2 Blocking Peptide
20-abx061157
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

MRG15 Blocking Peptide
20-abx061158
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

CADM1 Blocking Peptide
20-abx061159
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

APPBP2 Blocking Peptide
20-abx061160
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

CEP135 Blocking Peptide
20-abx061162
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

EIF3J Blocking Peptide
20-abx061163
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

MRPS22 Blocking Peptide
20-abx061164
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

RIMS4 Blocking Peptide
20-abx061167
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

RHOBTB3 Blocking Peptide
20-abx061168
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

OUTB1 Blocking Peptide
20-abx061170
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

NRBP1 Blocking Peptide
20-abx061171
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

GPR40 Blocking Peptide
20-abx061175
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

COX10 Blocking Peptide
20-abx061180
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

RAB34 Blocking Peptide
20-abx061185
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

RASD2 Blocking Peptide
20-abx061189
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

ALT2 Blocking Peptide
20-abx061190
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

DZIP3 Blocking Peptide
20-abx061191
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

CaMK4 Blocking Peptide
20-abx061202
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

Dematin Blocking Peptide
20-abx061203
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

TBX10 Blocking Peptide
20-abx061209
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

TAF5L Blocking Peptide
20-abx061210
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

PSKH1 Blocking Peptide
20-abx061211
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

ZNF24 Blocking Peptide
20-abx061212
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

EPHA1 Blocking Peptide
20-abx061213
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

GTF2H1 Blocking Peptide
20-abx061214
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

Recoverin Blocking Peptide
20-abx061215
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

BUD31 Blocking Peptide
20-abx061216
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

MKK4 Blocking Peptide
20-abx061217
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

ID4 Blocking Peptide
20-abx061218
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

FOXK1 Blocking Peptide
20-abx061221
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

TRIM25 Blocking Peptide
20-abx061223
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

DOK7 Blocking Peptide
20-abx061226
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

PIG3 Blocking Peptide
20-abx061227
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

ZNF397 Blocking Peptide
20-abx061229
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

ZNF596 Blocking Peptide
20-abx061231
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

ZNF785 Blocking Peptide
20-abx061232
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

ZNF668 Blocking Peptide
20-abx061233
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

BTBD6 Blocking Peptide
20-abx061234
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

CDK15 Blocking Peptide
20-abx061235
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

BEGAIN Blocking Peptide
20-abx061236
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

YTHDF1 Blocking Peptide
20-abx061237
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

Biocide werkzaamheid van tutine en de invloed ervan op immuuncellen en expressie van groeiremmende en neurogliale peptiden in Mythimna separata (Lepidoptera: Noctuidae)

Mythimna separata Walker (Lepidoptera: Noctuidae) is een van de belangrijkste plagen die ernstige schade aan graangewassen kan veroorzaken. De ontwikkeling van botanische insecticiden met een lage toxiciteit en hoge prestaties wordt de focus van nieuw onderzoek naar pesticiden om M. separata te bestrijden. Tutin, een sesquiterpeenlactonverbinding die wordt verkregen uit Coriaria sinica Maxim, een inheemse Chinese language language giftige plant, heeft een antivoedingsmiddel, absorptie en maagvergiftiging tegen een verscheidenheid aan plagen. Om het toxische impression van tutine op de larven van M. separata te begrijpen, wilden we hun anti-voedingsmiddel, mortaliteit, verlamming, gewichtsverandering bepalen en de verspreiding van M. separata hemocyten onder verschillende concentraties van tutinebehandeling onderzoeken.

Weefselverdeling van het immuun-geassocieerde gengroei-blokkerende peptide (GBP) en neuroglian peptide (Nrg) werd gedetecteerd door reverse transcriptie polymerase kettingreactie (PCR). Verder werd real-time kwantitatieve PCR uitgevoerd om de expressieprofielen van GBP en Nrg te bepalen na verschillende concentraties van tutine-stimulatie. Onze resultaten onthulden dat tutine significante anti-feedant en insecticide activiteiten, verlamming, gewichtsverlies voor M. separata vertoonde . Bovendien had tutine een significante invloed op de morfologie van hemocyten en versterkte het de expressie van GBP en Nrg in M. separata.

Van stress afgeleide reactieve zuurstofsoorten stellen hemocyten in staat om activator van groeiblokkerend peptide (GBP) -verwerkingsenzym af te geven

Insectencytokinegroeiblokkerend peptide (GBP) wordt gesynthetiseerd als een inactieve voorloper, proGBP genaamd, die normaal in een significante concentratie aanwezig is in de hemolymfe van dieren zonder stress (Hayakawa, 1990, 1991). Onder stressomstandigheden wordt proGBP onmiddellijk omgezet tot actief GBP door een serineprotease en males denkt dat dit een belangrijke eerste stap is voor insecten om het hoofd te bieden aan door stress veroorzaakte nadelige effecten by the use of GBP-geïnduceerde fysiologische veranderingen.

Het gedetailleerde mechanisme dat ten grondslag ligt aan de proteolytische verwerking van hemolymfe proGBP bij insecten onder stressomstandigheden blijft echter onbekend. Hier hebben we aangetoond dat proGBP-verwerking door ROS geïnduceerde afgifte van een eiwitachtige concern uit hemocyten vereist die het inactieve proGBP-verwerkingsenzym activeert. De afgifte van het activatoreiwit uit hemocyten wordt geïnitieerd door een verhoging van de cytoplasmatische Ca2 +  -concentratie, geïnduceerd door ROS. Daarom concludeerden we dat door stress geïnduceerde activering van proGBP ROS-afhankelijke stimulatie van een intracellulaire calciumsignaleringsroute in hemocyten vereist, gevolgd door afgifte van de hemocyt-eiwitachtige concern die specifiek het proGBP-verwerkingsenzym activeert.

Lipopolysacharide beïnvloedt het plasma en hersenen farmacokinetiek van subcutaan toegediende HsTX1 [R14a], Okay  V  1,3-blokkerende peptide

Okay<sub>V</sub>1.Three is een spanningsafhankelijk kaliumkanaal dat wordt opgereguleerd bij neuro-inflammatoire aandoeningen, zoals de ziekte van Alzheimer en de ziekte van Parkinson. HsTX1[R14A] is een krachtige en selectieve peptideblokker van Okay<sub>V</sub>1.Three met het potentieel om microgliale Okay<sub>V</sub>1.Three te blokkeren, maar de opname in de hersenen zal naar verwachting beperkt zijn vanwege de beperkende aard van de bloed-hersenbarrière. Om de perifere en hersenblootstelling te beoordelen , werd een LC-MS/MS-assay ontwikkeld om HsTX1[R14A]-concentraties in muizenplasma en hersenhomogenaat te kwantificeren die betrouwbaar en reproduceerbaar waren in het bereik van 6,7-66,7 nM (r<sup>2< /sup> = 0,9765) en 15-150 pmol/g (r<sup>2</sup> = 0,9984), respectievelijk.

Om te beoordelen of neuro-inflammatie de HsTX1[R14A]-dispositie beïnvloedde, kregen C57BL/6-muizen HsTX1[R14A] subcutaan (2 mg/kg) 24 uur na een intraperitoneale dosis Escherichia coli lipopolysaccharide (LPS), die vaak wordt gebruikt om neuro-inflammatie te induceren; hersen- en plasmaconcentraties van HsTX1[R14A] werden vervolgens gedurende 120 minuten gekwantificeerd. LPS-behandelingvertraagde de daling van de HsTX1[R14A]-plasmaconcentraties aanzienlijk, vermoedelijk als gevolg van een verminderde renale klaring, en leidde tot een substantiële opname van HsTX1[R14A] in de hersenen, vermoedelijk door verstoring van de inter-endotheliale tight junctions in de hersenen. Deze studie suggereert dat HsTX1[R14A] microglia kan bereiken in voldoende concentraties om Okay<sub>V</sub>1.Three te blokkeren bij neuro-inflammatoire aandoeningen, en daarom het potentieel heeft om neurodegeneratieve ziekten te verminderen.

Rat Uncoupling Protein 2, Mitochondrial (UCP2) ELISA Kit
RD-UCP2-Ra-96Tests 96 Tests
EUR 775

Human Uncoupling Protein 2, Mitochondrial (UCP2) ELISA Kit
DLR-UCP2-Hu-48T 48T
EUR 517
Description: A sandwich quantitative ELISA assay kit for detection of Human Uncoupling Protein 2, Mitochondrial (UCP2) in samples from tissue homogenates or other biological fluids.

Human Uncoupling Protein 2, Mitochondrial (UCP2) ELISA Kit
DLR-UCP2-Hu-96T 96T
EUR 673
Description: A sandwich quantitative ELISA assay kit for detection of Human Uncoupling Protein 2, Mitochondrial (UCP2) in samples from tissue homogenates or other biological fluids.

Rat Uncoupling Protein 2, Mitochondrial (UCP2) ELISA Kit
DLR-UCP2-Ra-48T 48T
EUR 549
Description: A sandwich quantitative ELISA assay kit for detection of Rat Uncoupling Protein 2, Mitochondrial (UCP2) in samples from tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Rat Uncoupling Protein 2, Mitochondrial (UCP2) ELISA Kit
DLR-UCP2-Ra-96T 96T
EUR 718
Description: A sandwich quantitative ELISA assay kit for detection of Rat Uncoupling Protein 2, Mitochondrial (UCP2) in samples from tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Human Uncoupling Protein 2, Mitochondrial (UCP2) ELISA Kit
RDR-UCP2-Hu-48Tests 48 Tests
EUR 544

Human Uncoupling Protein 2, Mitochondrial (UCP2) ELISA Kit
RDR-UCP2-Hu-96Tests 96 Tests
EUR 756

Rat Uncoupling Protein 2, Mitochondrial (UCP2) ELISA Kit
RDR-UCP2-Ra-48Tests 48 Tests
EUR 583

Rat Uncoupling Protein 2, Mitochondrial (UCP2) ELISA Kit
RDR-UCP2-Ra-96Tests 96 Tests
EUR 811

Human Uncoupling Protein 2 (UCP2) Control/blocking peptide #3
UCP23-P 100 ug
EUR 164

Mouse UCP2 shRNA Plasmid
20-abx973302
  • EUR 801.00
  • EUR 1121.00
  • 150 µg
  • 300 µg

UCP2 Recombinant Protein (Mouse)
RP182948 100 ug Ask for price

Substance P reversed sequence Peptide
20-abx266314
  • EUR 495.00
  • EUR 815.00
  • EUR 356.00
  • 10 mg
  • 25 mg
  • 5 mg

Erythropoietin Mimetic Peptide Sequence 20
H-4344.0001 1.0mg
EUR 454
Description: Sum Formula: C72H99N17O17S2; CAS# [203397-62-0] net

Erythropoietin Mimetic Peptide Sequence 20
H-4344.0005 5.0mg
EUR 1723
Description: Sum Formula: C72H99N17O17S2; CAS# [203397-62-0] net

UCP2 Antibody
1-CSB-PA299698
  • EUR 317.00
  • EUR 244.00
  • 100ul
  • 50ul
Description: A polyclonal antibody against UCP2. Recognizes UCP2 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:10-1:50

UCP2 Antibody
1-CSB-PA060040
  • EUR 222.00
  • EUR 195.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against UCP2. Recognizes UCP2 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: IHC, ELISA;IHC:1/100-1/300.ELISA:1/10000

UCP2 Antibody
1-CSB-PA025555EA01HU
  • EUR 317.00
  • EUR 335.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against UCP2. Recognizes UCP2 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC; Recommended dilution: IHC:1:20-1:200

UCP2 Antibody
1-CSB-PA025555GA01HU
  • EUR 597.00
  • EUR 333.00
  • 150ul
  • 50ul
Description: A polyclonal antibody against UCP2. Recognizes UCP2 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC

UCP2 Antibody
1-CSB-PA032095
  • EUR 317.00
  • EUR 244.00
  • 100ul
  • 50ul
Description: A polyclonal antibody against UCP2. Recognizes UCP2 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:2000-1:5000, IHC:1:25-1:100

UCP2 siRNA
20-abx938928
  • EUR 551.00
  • EUR 732.00
  • 15 nmol
  • 30 nmol

UCP2 siRNA
20-abx938929
  • EUR 551.00
  • EUR 732.00
  • 15 nmol
  • 30 nmol

UCP2 siRNA
20-abx905933
  • EUR 551.00
  • EUR 732.00
  • 15 nmol
  • 30 nmol

UCP2 Antibody
40280-100ul 100ul
EUR 252

UCP2 Antibody
ABD8626 100 ug
EUR 438

UCP2 Antibody
DF8626 200ul
EUR 304
Description: UCP2 Antibody detects endogenous levels of total UCP2.

UCP2 antibody
70R-21145 50 ul
EUR 435
Description: Rabbit polyclonal UCP2 antibody

UCP2 antibody
70R-UR002 100 ug
EUR 640
Description: Affinity purified Rabbit polyclonal UCP2 antibody

UCP2 antibody
70R-UR003 100 ug
EUR 640
Description: Affinity purified Rabbit polyclonal UCP2 antibody

UCP2 antibody
20R-UR001 100 ug
EUR 673
Description: Rabbit polyclonal UCP2 antibody

anti-UCP2
YF-PA15210 50 ug
EUR 363
Description: Mouse polyclonal to UCP2

anti-UCP2
YF-PA15211 50 ug
EUR 363
Description: Mouse polyclonal to UCP2

anti-UCP2
YF-PA15212 50 ug
EUR 363
Description: Mouse polyclonal to UCP2

anti-UCP2
YF-PA15213 100 ug
EUR 403
Description: Rabbit polyclonal to UCP2

Mouse C-Peptide ELISA Kit
RD-C-Peptide-Mu-48Tests 48 Tests
EUR 446

Mouse C-Peptide ELISA Kit
RD-C-Peptide-Mu-96Tests 96 Tests
EUR 615

Mouse C-Peptide ELISA Kit
DLR-C-Peptide-Mu-48T 48T
EUR 450
Description: A competitive inhibition quantitative ELISA assay kit for detection of Mouse C-Peptide in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Mouse C-Peptide ELISA Kit
DLR-C-Peptide-Mu-96T 96T
EUR 582
Description: A competitive inhibition quantitative ELISA assay kit for detection of Mouse C-Peptide in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Mouse C-Peptide ELISA Kit
RDR-C-Peptide-Mu-48Tests 48 Tests
EUR 465

Mouse C-Peptide ELISA Kit
RDR-C-Peptide-Mu-96Tests 96 Tests
EUR 643

(PPPPNAND)3 peptide (repeat-sequence peptide of the P. berghei circumsporozoite protein, CSP) control/blocking peptide
PPPP321-P 100 ug
EUR 164

(NANP)5 peptide (repeat-sequence peptide of the P. falciparum circumsporozoite protein, CSP) control/blocking peptide
NANP51-P 1 mg
EUR 347

UCP2 ELISA Kit (Mouse) (OKCD08189)
OKCD08189 96 Wells
EUR 1001
Description: Description of target: UCP are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation from ATP synthesis. As a result, energy is dissipated in the form of heat (By similarity).;Species reactivity: Mouse;Application: ELISA;Assay info: ;Sensitivity: < 0.059ng/mL

UCP2 ELISA Kit (Mouse) (OKEH05261)
OKEH05261 96 Wells
EUR 662
Description: Description of target: UCP are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation from ATP synthesis. As a result, energy is dissipated in the form of heat.;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.089 ng/mL

UCP2 ELISA Kit (Mouse) (OKAN05918)
OKAN05918 96 Wells
EUR 792
Description: Description of target: ;Species reactivity: Mouse;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.059 ng/mL

Ucp2 ORF Vector (Mouse) (pORF)
ORF060984 1.0 ug DNA
EUR 506

Influenza A virus (H5N1) matrix protein 2 hybrid sequence Control/blocking peptide
M2E11-P 100 ug
EUR 164

mouse Splunc2 Blocking Peptide
BF0461-BP 1mg
EUR 195

GLUT4 Blocking peptide (Mouse)
30R-AG010 100 ug
EUR 241
Description: A synthetic GLUT4 Blocking peptide for use as a blocking control in assays to test for specificity of GLUT4 antibody, catalog no. 70R-GR014

GLUT8 Blocking Peptide (Mouse)
30R-AG011 100 ug
EUR 241
Description: A synthetic GLUT8 Blocking peptide for use as a blocking control in assays to test for specificity of GLUT8 antibody, catalog no. 70R-GR008

(NVDP)4 peptide (minor repeat-sequence peptide of the P. falciparum circumsporozoite protein, CSP) control/blocking peptide
NVDP41-P 100 ug
EUR 164

(DRAAGQPAG)3 (repeat-sequence peptide of the P. vivax circumsporozoite protein, CSP) control/blocking peptide
DRAA31-P 100 ug
EUR 164

UCP2 cloning plasmid
CSB-CL025555HU-10ug 10ug
EUR 233
Description: A cloning plasmid for the UCP2 gene.

UCP2 Polyclonal Antibody
ES7475-100ul 100ul
EUR 279
Description: A Rabbit Polyclonal antibody against UCP2 from Human/Mouse/Rat. This antibody is tested and validated for IHC, WB, ELISA

UCP2 Polyclonal Antibody
ES7475-50ul 50ul
EUR 207
Description: A Rabbit Polyclonal antibody against UCP2 from Human/Mouse/Rat. This antibody is tested and validated for IHC, WB, ELISA

Anti-UCP2 antibody
STJ26031 100 µl
EUR 277
Description: Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. This gene is expressed in many tissues, with the greatest expression in skeletal muscle. It is thought to play a role in nonshivering thermogenesis, obesity and diabetes. Chromosomal order is 5'-UCP3-UCP2-3'.

UCP2 Polyclonal Antibody
ABP56476-003ml 0.03ml
EUR 158
Description: A polyclonal antibody for detection of UCP2 from Human, Mouse, Rat. This UCP2 antibody is for IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human UCP2

UCP2 Polyclonal Antibody
ABP56476-01ml 0.1ml
EUR 289
Description: A polyclonal antibody for detection of UCP2 from Human, Mouse, Rat. This UCP2 antibody is for IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human UCP2

UCP2 Polyclonal Antibody
ABP56476-02ml 0.2ml
EUR 414
Description: A polyclonal antibody for detection of UCP2 from Human, Mouse, Rat. This UCP2 antibody is for IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human UCP2

Anti-UCP2 Antibody
A02256-1 100ug/vial
EUR 294

UCP2 Rabbit pAb
A4178-100ul 100 ul
EUR 308

UCP2 Rabbit pAb
A4178-200ul 200 ul
EUR 459

UCP2 Rabbit pAb
A4178-20ul 20 ul
EUR 183

UCP2 Rabbit pAb
A4178-50ul 50 ul
EUR 223

UCP2 Polyclonal Antibody
A63760 100 µg
EUR 570.55
Description: fast delivery possible

Anti-UCP2 antibody
STJ96178 200 µl
EUR 197
Description: Rabbit polyclonal to UCP2.

UCP2 Conjugated Antibody
C40280 100ul
EUR 397

anti- UCP2 antibody
FNab09228 100µg
EUR 548.75
Description: Antibody raised against UCP2

Anti-UCP2 antibody
PAab09228 100 ug
EUR 386

Ucp2 sgRNA CRISPR Lentivector set (Mouse)
K4429201 3 x 1.0 ug
EUR 339

Nori® Mouse UCP2 ELISA Kit
GR117021 96-well
EUR 461

Mouse Lipin-1 Control/blocking peptide control/blocking peptide #1
LPN11-P 100 ug
EUR 164

Mouse Lipin-2 Control/blocking peptide control/blocking peptide #1
LPN21-P 100 ug
EUR 164

Mouse Lipin-3 Control/blocking peptide control/blocking peptide #1
LPN31-P 100 ug
EUR 164

Mouse Moesin control/blocking peptide
MSN11-P 100 ug
EUR 164

Mouse Klotho Control/blocking peptide
KL11-P 100 ug
EUR 164

Mouse CYP1B1 control/blocking peptide
CYP1B12-P 100 ug
EUR 164

Mouse Agouti Control/blocking peptide
AGO11-P 100 ug
EUR 164

Mouse AQP12 control/blocking peptide
AQP125-P 100 ug
EUR 152

CLDN6 Mouse mAb Blocking Peptide
BF8001-BP 1mg
EUR 195

Fibronectin Mouse mAb Blocking Peptide
BF9010-BP 1mg
EUR 195

HSP70 Mouse mAb Blocking Peptide
BF9012-BP 1mg
EUR 195

Angiopoietin 1 Blocking Peptide (Mouse)
30R-AA012 100 ug
EUR 256
Description: A synthetic Angiopoietin 1 Blocking peptide for use as a blocking control in assays to test for specificity of Angiopoietin 1 antibody, catalog no. 70R-AR004

PPAR Delta Blocking Peptide (Mouse)
30R-AC025 50 ug
EUR 251
Description: PPAR synthetic control neutralising peptide

C-Peptide Blocking Peptide
3277BP-50
EUR 153

Human, mouse, rat connexin 43 and 37 hemi-channel blocking peptide (GAP27 domain with conserved sequence SRPTEK)
Cx2703-P-1 1 mg
EUR 263

Human, mouse, rat connexin 43 and 37 hemi-channel blocking peptide (GAP27 domain with conserved sequence SRPTEK)
Cx2703-P-5 5 mg
EUR 773

UCP2 Antibody, HRP conjugated
1-CSB-PA025555EB01HU
  • EUR 317.00
  • EUR 335.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against UCP2. Recognizes UCP2 from Human. This antibody is HRP conjugated. Tested in the following application: ELISA

UCP2 Antibody, FITC conjugated
1-CSB-PA025555EC01HU
  • EUR 317.00
  • EUR 335.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against UCP2. Recognizes UCP2 from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

UCP2 Antibody, Biotin conjugated
1-CSB-PA025555ED01HU
  • EUR 317.00
  • EUR 335.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against UCP2. Recognizes UCP2 from Human. This antibody is Biotin conjugated. Tested in the following application: ELISA

Polyclonal UCP2 Antibody (Internal)
APR10651G 0.05mg
EUR 484
Description: A polyclonal antibody raised in Goat that recognizes and binds to Human UCP2 (Internal). This antibody is tested and proven to work in the following applications:

Rat UCP2 shRNA Plasmid
20-abx985837
  • EUR 801.00
  • EUR 1121.00
  • 150 µg
  • 300 µg

Human UCP2 shRNA Plasmid
20-abx955026
  • EUR 801.00
  • EUR 1121.00
  • 150 µg
  • 300 µg

UCP2 ELISA KIT|Human
EF006165 96 Tests
EUR 689

Human UCP2 ELISA Kit
ELA-E2066h 96 Tests
EUR 824

UCP2 Recombinant Protein (Human)
RP033886 100 ug Ask for price

UCP2 Recombinant Protein (Rat)
RP235745 100 ug Ask for price

Mouse Uncoupling Protein 2, Mitochondrial (UCP2) Protein
20-abx069604
  • EUR 746.00
  • EUR 300.00
  • EUR 2346.00
  • EUR 899.00
  • EUR 537.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Ucp2 sgRNA CRISPR Lentivector (Mouse) (Target 1)
K4429202 1.0 ug DNA
EUR 154

Ucp2 sgRNA CRISPR Lentivector (Mouse) (Target 2)
K4429203 1.0 ug DNA
EUR 154

Ucp2 sgRNA CRISPR Lentivector (Mouse) (Target 3)
K4429204 1.0 ug DNA
EUR 154

UCP2 Protein Vector (Mouse) (pPB-C-His)
PV243934 500 ng
EUR 603

UCP2 Protein Vector (Mouse) (pPB-N-His)
PV243935 500 ng
EUR 603

UCP2 Protein Vector (Mouse) (pPM-C-HA)
PV243936 500 ng
EUR 603

UCP2 Protein Vector (Mouse) (pPM-C-His)
PV243937 500 ng
EUR 603

Mouse Peptide YY (PYY) control/blocking peptide # 1
PYY11-P 100 ug
EUR 164

Canine C-Peptide ELISA Kit
RD-C-Peptide-c-48Tests 48 Tests
EUR 533

Canine C-Peptide ELISA Kit
RD-C-Peptide-c-96Tests 96 Tests
EUR 740

Human C-Peptide ELISA Kit
RD-C-Peptide-Hu-48Tests 48 Tests
EUR 387

Human C-Peptide ELISA Kit
RD-C-Peptide-Hu-96Tests 96 Tests
EUR 532

Rat C-Peptide ELISA Kit
RD-C-Peptide-Ra-48Tests 48 Tests
EUR 465

Rat C-Peptide ELISA Kit
RD-C-Peptide-Ra-96Tests 96 Tests
EUR 643

Canine C-Peptide ELISA Kit
DLR-C-Peptide-c-48T 48T
EUR 527
Description: A competitive inhibition quantitative ELISA assay kit for detection of Canine C-Peptide in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Canine C-Peptide ELISA Kit
DLR-C-Peptide-c-96T 96T
EUR 688
Description: A competitive inhibition quantitative ELISA assay kit for detection of Canine C-Peptide in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Human C-Peptide ELISA Kit
DLR-C-Peptide-Hu-48T 48T
EUR 398
Description: A competitive inhibition quantitative ELISA assay kit for detection of Human C-Peptide in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Human C-Peptide ELISA Kit
DLR-C-Peptide-Hu-96T 96T
EUR 511
Description: A competitive inhibition quantitative ELISA assay kit for detection of Human C-Peptide in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Rat C-Peptide ELISA Kit
DLR-C-Peptide-Ra-48T 48T
EUR 467
Description: A competitive inhibition quantitative ELISA assay kit for detection of Rat C-Peptide in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Rat C-Peptide ELISA Kit
DLR-C-Peptide-Ra-96T 96T
EUR 605
Description: A competitive inhibition quantitative ELISA assay kit for detection of Rat C-Peptide in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Canine C-Peptide ELISA Kit
RDR-C-Peptide-c-48Tests 48 Tests
EUR 557

Canine C-Peptide ELISA Kit
RDR-C-Peptide-c-96Tests 96 Tests
EUR 774

Human C-Peptide ELISA Kit
RDR-C-Peptide-Hu-48Tests 48 Tests
EUR 404

Human C-Peptide ELISA Kit
RDR-C-Peptide-Hu-96Tests 96 Tests
EUR 556

Rat C-Peptide ELISA Kit
RDR-C-Peptide-Ra-48Tests 48 Tests
EUR 486

Rat C-Peptide ELISA Kit
RDR-C-Peptide-Ra-96Tests 96 Tests
EUR 672

CD39 Blocking Peptide
P10103 20 ug Blocking Peptide
EUR 146

P2X3 Blocking Peptide
P10108 100 ug Blocking Peptide
EUR 146

CXCL1 Blocking Peptide
20-abx061039
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

p21 Blocking Peptide
20-abx061043
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

Dyskerin Blocking Peptide
20-abx061050
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

ZNF265 Blocking Peptide
20-abx061051
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

CDK11B Blocking Peptide
20-abx061053
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

HMGB2 Blocking Peptide
20-abx061056
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

ZFP36L2 Blocking Peptide
20-abx061059
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

CBP20 Blocking Peptide
20-abx061060
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

FOXE3 Blocking Peptide
20-abx061063
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

CBFB Blocking Peptide
20-abx061064
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

MAPKAPK3 Blocking Peptide
20-abx061065
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

MOB3C Blocking Peptide
20-abx061067
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

DPF2 Blocking Peptide
20-abx061068
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

TAF15 Blocking Peptide
20-abx061069
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

FAM84B Blocking Peptide
20-abx061070
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

GTF2IRD1 Blocking Peptide
20-abx061071
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

COL19A1 Blocking Peptide
20-abx061072
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

CYP2W1 Blocking Peptide
20-abx061073
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

RAD21 Blocking Peptide
20-abx061075
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

PSMC3 Blocking Peptide
20-abx061076
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

PSMD11 Blocking Peptide
20-abx061077
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

MRPS9 Blocking Peptide
20-abx061078
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

MRPL41 Blocking Peptide
20-abx061079
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

MRPL48 Blocking Peptide
20-abx061080
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

RPS12 Blocking Peptide
20-abx061081
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

RPS13 Blocking Peptide
20-abx061082
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

ACSS1 Blocking Peptide
20-abx061084
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

AKR1C2 Blocking Peptide
20-abx061085
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

ACER3 Blocking Peptide
20-abx061086
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

ATP5I Blocking Peptide
20-abx061087
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

ATP5C1 Blocking Peptide
20-abx061088
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

CNTROB Blocking Peptide
20-abx061089
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

CEP78 Blocking Peptide
20-abx061090
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

DMGDH Blocking Peptide
20-abx061093
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

EIF3D Blocking Peptide
20-abx061095
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

FUBP3 Blocking Peptide
20-abx061096
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

GHITM Blocking Peptide
20-abx061097
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

SAR1B Blocking Peptide
20-abx061098
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

NXPH3 Blocking Peptide
20-abx061101
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

PP15 Blocking Peptide
20-abx061102
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

LONP2 Blocking Peptide
20-abx061104
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

PEX10 Blocking Peptide
20-abx061105
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

PABPC5 Blocking Peptide
20-abx061106
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

PRPF39 Blocking Peptide
20-abx061107
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

PPM1K Blocking Peptide
20-abx061108
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

RSAD1 Blocking Peptide
20-abx061109
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

Renin Blocking Peptide
20-abx061110
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

SH2D2A Blocking Peptide
20-abx061113
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

SCN4B Blocking Peptide
20-abx061114
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

SFRS15 Blocking Peptide
20-abx061115
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

TCEAL1 Blocking Peptide
20-abx061116
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

TMBIM4 Blocking Peptide
20-abx061117
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

WIPF1 Blocking Peptide
20-abx061118
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

ZFYVE19 Blocking Peptide
20-abx061119
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

ZNT1 Blocking Peptide
20-abx061120
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

BNIP3 Blocking Peptide
20-abx061122
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

SHIP2 Blocking Peptide
20-abx061126
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

CD248 Blocking Peptide
20-abx061132
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

CD225 Blocking Peptide
20-abx061133
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

CD276 Blocking Peptide
20-abx061134
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

CD300d Blocking Peptide
20-abx061135
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

GPR10 Blocking Peptide
20-abx061136
  • EUR 286.00